The Single Best Strategy To Use For ceesdekker
The Single Best Strategy To Use For ceesdekker
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Applying solitary-molecule optical and AFM imaging and power-spectroscopy techniques, we request to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits incorporate:
It had been only in the nineties although, when nanotechnology had Sophisticated into a stage where by solitary molecules can be manipulated, that the very first experimental devices started to appear.
Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
That is a aspiration of mine and we established to work that has a scrumptious dose of naivety. This is often something that will most likely generate magnificent ends in the for a longer period phrase, but that does not subject. You should not only want to work around the thoughts of tomorrow, but will also around the inquiries of your day right after tomorrow.’
Our exploration ranges within the biophysics of DNA to artificial cells and further than. Be sure to take a look underneath for the spectrum of our latest initiatives.
A lot of linked developments adopted, wherever our team founded distinctive transistor variants such as single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled several transistors into tiny proof-of-principle electronic circuits.
Researching ceesdekker.net DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
The rotors harness Electrical power from a nanoscale h2o and ion flow which is created by a static chemical or electrochemical likely gradient inside the nanopore, which happen to be recognized by way of a salt gradient or utilized voltage, respectively. These artificial nanoengines self-organize and work autonomously in physiological circumstances, suggesting methods to developing energy-transducing motors at nanoscale interfaces.
Bulk-surface area coupling identifies the mechanistic link involving Min-protein styles in vivo and in vitro
[fourteen] In 2005 Dekker became linked to Netherlands-broad conversations about Intelligent Layout, a movement that he has considering the fact that Obviously distanced himself from. Dekker advocates that science and faith aren't in opposition but is often harmonized.
Cees Dekker is Distinguished University Professor at TU Delft. Qualified being a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes inside the 1990s. Given that 2000, he moved to single-molecule biophysics and nanobiology. His current investigate focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, particularly SMC motor protein; and (iii) creating a dwelling artificial cell from lifeless molecules. Dekker is definitely an elected member of your KNAW and fellow into the APS and the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)